Imaging Considerations In Arterial Ischaemic Stroke

Dynamic cerebral autoregulation is globally impaired after an ischaemic stroke 1 2 3 PaCO2: ↑CO2 changes periarteriolar pH, reduces vascular resistance and increases CBF PaO2: by unknown mechanisms, PaO2 falling below 50 mmHg leads to exponentially increased CBF MAP: Stable cerebral blood flow is maintained between 70 and 150 mmHg Cerebral Autoregulation MechanismsCerebral blood flow (CBF) is usually maintained around 50ml/100g/minThe brain can modulate its blood flow through vasodilatation and vasoconstriction.This is automatic and is influenced by metabolic demands e.g.