Cohort study observes cognitive decline linked to cumulative anticholinergic and sedative drug exposure in older adults, highlighting modifiable risk factors.
Long-term exposure to anticholinergic and sedative drugs could be a modifiable risk factor for cognitive decline. The objective of this study was to measure the association between previous cumulative anticholinergic and sedative drug exposure (Drug Burden Index) and cognitive decline.
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Reallon et al. (2024) studied this question.
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