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July 22, 2024

Supplementary Video S1 from Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images

Daniel M. Spagnolo Yousef Al‐Kofahi Peihong Zhu Timothy R. Lezon Albert Gough Andrew M. Stern Adrian V. Lee Fiona Ginty Brion Sarachan D. Lansing Taylor S. Chakra Chennubhotla

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Key Points

Quantitative evaluation of spatial intratumoral heterogeneity is enabled by the THRIVE computer resource using multiplexed fluorescence images.
Multiplexed fluorescence images capture cellular patterns directly, and the resource supports systematic measurement of tumor microenvironments.
Technical implementation of the THRIVE computer resource aids image processing, which may enable reproducible profiling across laboratory studies.

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Implication

Technical report demonstrates THRIVE computer resource for spatial intratumoral heterogeneity, highlighting computational multiplexed image analysis.

Abstract

THRIVE computer resource.

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Cite This Study

Spagnolo et al. (2024) studied this question.

synapsesocial.com/papers/68e5f858b6db64358758ca97 https://doi.org/10.1158/0008-5472.26352438.v1

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Video S1 from Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images2024
2Data from Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images2024
3Supplementary Figure S7 from Trackable Intratumor Microdosing and Spatial Profiling Provide Early Insights into Activity of Investigational Agents in the Intact Tumor Microenvironment2024
4Supplementary Figure S7 from Trackable Intratumor Microdosing and Spatial Profiling Provide Early Insights into Activity of Investigational Agents in the Intact Tumor Microenvironment2024
5Supplementary Figure S2 from The Web-Based Portal SpatialTME Integrates Histological Images with Single-Cell and Spatial Transcriptomics to Explore the Tumor Microenvironment2024

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