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July 19, 2024F1000ResearchOpen Access

A guide to selecting high-performing antibodies for Synaptotagmin-1 (Uniprot ID P21579) for use in western blot, immunoprecipitation, immunofluorescence and flow cytometry

Michael Biddle Charles Alende Maryam Fotouhi Carolyn Jones Riham Ayoubi Kathleen Southern Carl Laflamme Harvinder Virk

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Abstract

Synaptotagmin-1 is a synaptic vesicle transmembrane protein that senses calcium influx via its tandem C2-domains, triggering synchronous neurotransmitter release. Disruption to

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Biddle et al. (2024) studied this question.

synapsesocial.com/papers/68e5fc6fb6db64358759014a https://doi.org/10.12688/f1000research.154034.1

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