Assessment of the harmlessness of a medicinal enterosorbent based on amorphous silicon dioxide

Veterinary enterosorbents play an important role in veterinary practice. The aim of the study was to assess the toxicity of a sorbent based on amorphous silicon dioxide (enterosorbent ADC) obtained from rice husks, which are waste products of the rice processing industry and enterosorbent Zooverad obtained from vermiculite, on the body of laboratory rats. Nonlinear rats from the nursery of the Russian Academy of Medical Sciences "Rappolovo" were used for the experiment. The live weight of animals is 40-80 g. 3 groups of animals with 20 rats each were formed. Group No. 1 received the basic diet and enterosorbent based on amorphous silicon dioxide (ADC), group No. 2 – the basic diet and Animal feed, group No. 3 – the control, only the basic diet. The results were evaluated by the live weight of the animals, their behavior, clinical condition, according to the results of hematological studies, pathoanatomical autopsy and massometry of the internal organs of rats.