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Preclinical analysis observes altered lung volumes in a mouse model of allergic inflammation, indicating translational relevance for understanding human asthma.
Air trapping, often attested in humans by elevated residual volume (RV) and ratio of RV on total lung capacity (RV/TLC), is frequently observed in asthma. Confirming these alterations in experimental asthma would be important for translational purposes. Herein, lung volumes were investigated in a mouse model of pulmonary allergic inflammation.
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Rojas‐Ruiz et al. (2024) studied this question.
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