Current Status of Breeding of Avermectin-producing Bacteria

Avilamycin, also known as Peomycin, is a product of ventilated fermentation of Streptomyces viridochromogene. The aim of this paper is to provide a comprehensive overview of the current status of breeding avilamycin-producing bacteria and to discuss in depth their physicochemical properties, breeding techniques, and future development directions and strategies. Modern biotechnological tools, such as gene editing and genomics analysis, were used to accelerate the breeding progress of avilamycin with a view to realizing further improvement in its yield and quality.