Hypoxia score associated with significant differences in microbial populations in colorectal cancer. A, Volcano plot of microbes from ORIEN and TCGA tumors showing strain differences when tumors are stratified by high vs. low hypoxia scores (tertiles). B, Fold change of microbes that show hypoxic enrichment in both ORIEN and TCGA datasets. XRT, X-ray therapy.
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Benej et al. (2024) studied this question.
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