Sea urchin-like Ni 3 (HITP) 2 as the substrate of molecular imprinted polymer: the voltammetric mechanism for sensitive detection of dopamine

Abstract As a neurotransmitter, dopamine plays an extremely important role in human body. Tracking the amount of dopamine is essential to keep health. An electrochemical sensor composed of conductive metal-organic framework [Ni3(HITP)2] and molecular imprinted polymers (MIP) is fabricated to detect dopamine. Ni3(HITP)2 promotes electrons transfer due to the structure of in-plane charge delocalization and layered expansion conjugation. The combination of MIP with Ni3(HITP)2 improves the selectivity and conductivity, exhibiting a wide detection range (0.06~200 µM) and a lower detection limit (0.109 µM). The kinetic mechanism on the electrode surface is an adsorption controlled process, with the equal number of electrons and protons participating in oxidation in the electrocatalytic process of catechol converting to o-quinone.