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July 2, 2024Open Access

Supplementary Fig. S9 from Small Extracellular Vesicle piR-hsa-30937 Derived from Pancreatic Neuroendocrine Neoplasms Upregulates CD276 in Macrophages to Promote Immune Evasion

Yuan Zhong Ye Tian Yan Wang Jian’an Bai Qin Long Lijun Yan Zhihui Gong Wei Gao Qiyun Tang

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Abstract

Supplementary Fig. S9 PNEN cell-derived sEV piR-hsa-30937 is transferred to macrophages and drives CD276 expression by targeting PTEN to activate the AKT signaling pathway. CD276+ macrophages suppress T-cell immunity and promote PNEN immune evasion and progression.

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Cite This Study

Zhong et al. (2024) studied this question.

synapsesocial.com/papers/68e61b74b6db6435875ae03a https://doi.org/10.1158/2326-6066.26144575.v1

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Fig. S9 from Small Extracellular Vesicle piR-hsa-30937 Derived from Pancreatic Neuroendocrine Neoplasms Upregulates CD276 in Macrophages to Promote Immune Evasion2024
2Supplementary Fig. S1 from Small Extracellular Vesicle piR-hsa-30937 Derived from Pancreatic Neuroendocrine Neoplasms Upregulates CD276 in Macrophages to Promote Immune Evasion2024
3Supplementary Fig. S1 from Small Extracellular Vesicle piR-hsa-30937 Derived from Pancreatic Neuroendocrine Neoplasms Upregulates CD276 in Macrophages to Promote Immune Evasion2024
4Supplementary Fig. S4 from Small Extracellular Vesicle piR-hsa-30937 Derived from Pancreatic Neuroendocrine Neoplasms Upregulates CD276 in Macrophages to Promote Immune Evasion2024
5Supplementary Fig. S4 from Small Extracellular Vesicle piR-hsa-30937 Derived from Pancreatic Neuroendocrine Neoplasms Upregulates CD276 in Macrophages to Promote Immune Evasion2024

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Supplementary Fig. S5 from Small Extracellular Vesicle piR-hsa-30937 Derived from Pancreatic Neuroendocrine Neoplasms Upregulates CD276 in Macrophages to Promote Immune Evasion2024
Supplementary Fig. S5 from Small Extracellular Vesicle piR-hsa-30937 Derived from Pancreatic Neuroendocrine Neoplasms Upregulates CD276 in Macrophages to Promote Immune Evasion2024
Supplementary Fig. S7 from Small Extracellular Vesicle piR-hsa-30937 Derived from Pancreatic Neuroendocrine Neoplasms Upregulates CD276 in Macrophages to Promote Immune Evasion2024