Supplementary Figure 5 from Melanoma Clonal Heterogeneity Leads to Secondary Resistance after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes

Supplementary Figure 5. Reactivity assay of TIL product to the primary tumor. CD3+ T cells from the TIL product were tested for intracellular cytokine upregulation against a tumor cell line (TCL) derived from the resected lesion. Anti-CD3/CD28 stimulation was used as positive control. As a negative control, we used HLA blockade.