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Insulin sensitivity, as a key measure of metabolic health and hormonal balance, plays a crucial role in metabolic disease with impaired insulin signaling also described as insulin resistance (Zhao et al., 2023). The problem of insulin resistance as a hormonal imbalance due to a changed metabolism is gaining increasing international attention and can be referred to as new epidemic of the 21st century (Zyoud et al., 2022). Insulin resistance affects an estimated 40% of people aged 18–48. Half of the affected people are not overweight (Parcha et al., 2022).
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