Supplementary table 2: Full list of genes whose overexpression was selectively toxic in the presence of LB-100 in HT-29 cells in the CRISPRa screen FDR smaller or equal to 0.25 and log2 fold change smaller or equal to -1 in treated/untreated comparison were criteria for hit selection.
No takes yet. Share an insight, caveat, or question.
Dias et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: