P-061 Effect of Varicocelectomy on fertility potential and pregnancy outcome: results of a large cohort from a tertiary medical center

Abstract Study question Does varicocelectomy improve semen parameters, hormones 0. 05 was considered statically significant. Main results and the role of chance A 2171 participants were included. The mean age ± SD of the study population was 33. 65 ± 8. 54 years. Their mean right testicular size, left testicular size, right vein size, and left vein size were 14. 38 ± 4. 56, 13. 46 ± 3. 49, 2. 47±0. 79 & 3. 99 ±1. 33 respectively. When subdividing them by grade of varicocele, on the right side, grades 1, 2, and 3 were detected in 692 (31. 9%), 491 (22. 6%), and 63 (2. 9%), respectively. While on the left side, grades 1, 2, and 3 varicoceles were detected in 303 (13. 9%), 999 (46%) & 867 (39. 9%), respectively. Indication for surgery was pain (37%, primary infertility (42. 9%), secondary infertility (18. 3%), and others (3. 6%). The majority performed unilateral varicocelectomy (1776 81. 8%), while 396 (18. 2%) underwent bilateral varicocelectomy. Varicocelectomy significantly improved sperm count, total & progressive motility & DNA fragmentation. Pregnancy outcomes improved postoperatively for both spontaneous (32. 3%) & assisted reproduction (25. 2%). No significant change was found in hormones postoperatively. Limitations, reasons for caution Retrospective study, single center experience. Wider implications of the findings It is important in patients’ counselling & choose the best management for this group of patients. Trial registration number NA