Ss32-01 Role of the Poison Control and Pharmacovigilance Centre of Morocco (Capm) in the Management of Occupational Poisoning

Objective To present the role of the CAPM in the management of poisoning cases including the professional cases. Methods We focused on the methods and tools deployed by the CAPM for the toxicovigilance operational process and conducted a retrospective study of cases of occupational poisoning declared to the CAPM between 1980 and 2020. Results The toxicovigilance process adopted by the CAPM is based on six steps: collection of cases, analysis of cases, build of a database, detection of signals and their validation in alerts, and finally, minimization actions risks. The study of the CAPM database made it possible to count a total of 219,770 reports of poisoning cases excluding scorpion bites and envenomations between 1980 and 2020; among them professional poisonings represented 0.5% (1020 cases). These cases were collected from three sources, mainly by call centre available 24h, the consultation dedicated to heavy metal poisoning, or via the emergency toxicology laboratory which monitors cases of occupational heavy metal poisoning. The management of poisoning cases is essentially based on the use of antidotes available at the CAPM antidote centre. Conclusion The CAPM has a sustainable toxicovigilance system, responsive and capable of monitoring the profile of poisonings in all circumstances from its information system. However, the under-reporting of cases of occupational poisoning blocks its health vigilance function in this field.