Biphasic Synovial Sarcoma of Iliac Blade: Approach to a Rare Disease

Introduction: Synovial sarcoma (SS) is a high-grade, rare variant of soft tissue sarcoma (STS). Synovial sarcoma accounts for only 5%-10% of all soft tissue sarcomas. It is a rare malignant type. The biphasic subtype is even lesser known than the monophasic subtype. SS is common around joint cavities in the extremities, but can be present elsewhere in the body. : Rare disease approach Aims & Objectives ,Multi-disciplinary treatment, To assess post-operative radiotherapy outcome, Long-term complication assessment A 49-year-old woman Discussion: presented with a biphasic SS tumor of the lower abdominal arising from the right Iliac blade. Our case has been treated as a local disease with a multidisciplinary therapeutic approach. As a result, our patient has been disease-free for two years and, during that time, has achieved an acceptable quality of life. We discuss the pertinent clinical and surgical ndings of this rare biphasic SS tumor in this report. Tumor staging and therapeutic management are usually clear for a localized disease, but the proper management at the metastatic stage can be unclear. According to the literature, the histologic presence of an SS tumor thrombus affects tumor staging, making it unclear whether the tumor stage corresponds to localized or metastatic disease. Treatment for localized SS typically consists of a combination of surgery, radiotherapy (RT) and, in some cases, chemotherapy. Adjuvant therapy in localized SS shows a response rate >65% for chemotherapy and >90% for RT. Nonetheless, the exact benet of administering systemic therapy once SS is nonlocalized is controversial. In a localized biphasic SS tumor surgical excision followed by radiation Conclusion: can cause miracle and also recurrence chances decrease. Early diagnosis and prompt treatment is the key for disease free survival.