Role of Integrins in Human Sperm Cells on the Reproduction Process

Ovum and spermatozoa cells, namely male and female reproductive cells that unite at the time of fertilization, are synchronized molecular events that occur sequentially. Apart from being present in the egg cell, adhesion molecules called integrins are also involved in this molecular process. However, recently, these integrins have also been found in spermatozoa cells, especially in the head and tail areas. Because this problem is intended as an introduction to the laboratory which is part of the thesis research, the method used in this research is a literature review whose publication age is not more than 10 years. Research findings indicate that integrins play a crucial role in egg-sperm recognition, their interaction, and fusion, potentially addressing infertility issues in couples of reproductive age.