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Clinical vignette reveals squamous cell carcinoma linked to chronic inflammation in hidradenitis suppurativa, emphasizing detection challenges.
While chronic inflammation is a well-established risk factor for carcinogenesis, the varied cutaneous manifestations of long-standing hidradenitis suppurativa (HS) can delay early detection of squamous cell carcinoma (SCC). Here, we present the clinical vignette of a patient with rapidly progressive treatment refractory HS paired with striking interval imaging demonstrating the development of superimposed cutaneous SCC.
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Boyle et al. (2025) studied this question.
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