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Shows artemisinin extracts attenuate myocardial remodeling in a heart failure model, highlighting potential therapeutic value against cardiac fibrosis.
Artemisinin and its derivatives, the well-known anti-malarial drugs extracted from traditional Chinese medicine, Artemisia annua, have been implicated in treating fibrotic diseases. However, whether artemisinin affects cardiac fibrosis in the pathogenesis of heart failure is still unknown. This study aimed to evaluate the possible effects of artemisinin on cardiac function and myocardial fibrosis in the heart failure model and to explore the underlying mechanisms.
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Ma et al. (2024) studied this question.
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