Metaplastic breast carcinoma with squamous differentiation: report of nine cases

Breast metaplastic carcinomas are a rare form of malignancy that exhibit epithelial and sarcomatoid components, including primary squamous cell carcinoma. Primary breast SCC and tumors with squamous differentiation are subtypes of breast metaplastic cancer. The prevalence of primary squamous cell carcinoma (PSCC) of the breast is estimated to be between 0.06% and 0.2% of all breast cancers, and less than 0.1% of invasive breast cancers. At our Cancer Research Center, we have managed and treated 9 patients with PSCC aged between 24-67, and all of them except one were of reproductive age, out of a total of 4000 breast cancer cases during the last two years.