Integrative Genetic Variation, DNA Methylation, and Gene Expression Analysis of Escitalopram and Aripiprazole Treatment Outcomes in Depression: A CAN-BIND-1 Study

Farhana Islam; Amanda Lisoway; Edward Oh; Laura M. Fiori; Leen Magarbeh; Samar S. M. Elsheikh; Helena K. Kim; Stefan Kloiber; James L. Kennedy; Benício N. Frey; Roumen Milev; Cláudio N. Soares; Sagar V. Parikh; Franca Placenza; Stefanie Hassel; Valerie H. Taylor; Francesco Leri; Pierre Blier; Rudolf Uher; Faranak Farzan; Raymond W. Lam; Gustavo Turecki; Jane A. Foster; Susan Rotzinger; Sidney H. Kennedy; Daniel J. Müller

doi:10.1055/a-2313-9979

Ask about this paper

Answers are grounded in this paper and cite their sources.

Abstract

Little is known about the interplay between genetics and epigenetics on antidepressant treatment (1) response and remission, (2) side effects, and (3) serum levels. This study explored the relationship among single nucleotide polymorphisms (SNPs), DNA methylation (DNAm), and mRNA levels of four pharmacokinetic genes,

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Islam et al. (2024) studied this question.

synapsesocial.com/papers/68e635d4b6db6435875c750e https://doi.org/10.1055/a-2313-9979

View at Publisher

Ask AI

Bookmark

Share

Integrative Genetic Variation, DNA Methylation, and Gene Expression Analysis of Escitalopram and Aripiprazole Treatment Outcomes in Depression: A CAN-BIND-1 Study

Ask about this paper

Abstract

Discussion

Cite This Study

Integrative Genetic Variation, DNA Methylation, and Gene Expression Analysis of Escitalopram and Aripiprazole Treatment Outcomes in Depression: A CAN-BIND-1 Study

Ask about this paper

Abstract

Discussion

Cite This Study

Keep reading

Keep reading