Genetic analysis shows favorable fertility outcomes in infertile males carrying DNAH12 variants, suggesting effective clinical management using intracytoplasmic sperm injection.
Male infertility is a major concern affecting reproductive health. Biallelic deleterious variants of most DNAH gene family members have been linked to male infertility, with intracytoplasmic sperm injection (ICSI) being an efficacious way to achieve offspring. However, the association between
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Geng et al. (2024) studied this question.
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