Non-Hodgkin's Lymphoma of the Palatine Tonsil

Lymphoma is the second most common malignant tumor of the head and neck after squamous cell carcinoma. Involvement of the tonsils is relatively rare. Non-Hodgkin's lymphoma is the most frequent histological type. Unilateral tonsillar hypertrophy is the most common manifestation. Histopathology confirms the diagnosis. Our study includes thirteen cases of tonsillar lymphoma over a seven-year period, from January 2017 to December 2023. Cervical lymphadenopathy was present at the time of diagnosis in 62% of cases. Distant metastases were present in 69% of cases. The chemotherapy protocol used in our series was R-CHOP. A complete remission was observed in 62% of cases over a five-year follow-up period. Tonsillar lymphoma is an aggressive tumor, and tonsillar biopsy or tonsillectomy should be performed urgently in cases of suspected malignancy.