⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

June 21, 2024Journal of Personalized MedicineOpen Access

Genetic Variation in ABCB1, ADRB1, CYP3A4, CYP3A5, NEDD4L and NR3C2 Confers Differential Susceptibility to Resistant Hypertension among South Africans

Jonathan N. Katsukunya Erika Jones Nyarai D. Soko Dirk Blom Phumla Sinxadi Brian Rayner Collet Dandara

View Full Paper

Ask AI

Bookmark

Share

Abstract

Resistant hypertension (RHTN) prevalence ranges from 4 to 19% in Africa. There is a paucity of data on the role of genetic variation on RHTN among Africans. We set out to investigate the role of polymorphisms in

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Katsukunya et al. (2024) studied this question.

synapsesocial.com/papers/68e63c23b6db6435875ce603 https://doi.org/10.3390/jpm14070664

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Hypertension in African Populations: Review and Computational Insightssystematic_review · 2021 · 26 citations
2High Frequency of Variants of Candidate Genes in Black Africans with Low Renin-Resistant Hypertensioncross-sectional · 2016 · 61 citations
3Hypertension pharmacogenetics and limitations in Africa – a focus on the ACE, AGTR1 and CYP2C9 genesReview · 2026 · 1 citations
4Genetic Factors Contributing to the Pathogenesis of Essential Hypertension in Two African Populations2024 · 2 citations
5Genetic Factors Contributing to the Pathogenesis of Essential Hypertension in Two African Populations2024 · 8 citations

GENETIC FACTORS CONTRIBUTING TO THE PATHOGENESIS OF ESSENTIAL HYPERTENSION IN TWO AFRICAN POPULATIONS2024
Genetic Variation in Hydrochlorothiazide Response‐Related Genes Among Hypertensive Individuals in Soweto, South Africa2025
Genetic factors contributing to hypertension in African‐based populations: A systematic review and meta‐analysis2018
Clinical Decision Support Systems in Laboratory Medicine: Where Do We Stand Today and What Challenges Remain? A Systematic ReviewJournal of Personalized Medicine · 2026
Finerenone and SGLT2 Inhibitors in Cardiorenal Disease: A Phenotype-Based Approach to NephroprotectionJournal of Personalized Medicine · 2026

More from Journal of Personalized Medicine

More from University of Cape Town

More from South African Medical Research Council

More from Groote Schuur Hospital

More from Harare Institute of Technology