Surface plasmon resonance detections based on phase changes have demonstrated superior sensitivities over the intensity, spectral and angular methods due to the singularity effect (abrupt change of phase value) observed at resonance. The Goos–Hänchen effect, a higher first order derivative of the phase, can be observable as a lateral displacement of the reflected wave at total internal reflection and magnified by the surface plasmons. The GH sensitivity can be further improved through the addition of a phase change material nanolayer beneath the gold. Vanadium dioxide (VO2) belongs to the family of phase change materials that exhibit reversible insulator-metal behavior when heated above 68℃. Adding a thin layer of VO2 below the metal proved to theoretically enhance the sensitivity of a conventional gold-based surface plasmon biosensor (up to 28 times of improvement in comparison with the bare gold configuration).
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Youssef et al. (2024) studied this question.
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