Photobiomodulation (PBM) utilizes light to stimulate cellular responses in medical and therapeutic fields. This study investigates how light probe design influences tissue penetration. Factors like spot size, geometry, and materials were explored. Monte Carlo simulations and experiments were performed in tissue phantoms and volunteers. Results reveal how probe design optimization can enhance PBM's safety and efficacy, providing insights for personalized treatment protocols. Understanding light interactions in biological tissues is vital for tailoring therapy to individual patients and specific equipment.
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Fortunato et al. (2024) studied this question.
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