The Facility for Rare Isotope Beams (FRIB) is a major nuclear physics facility for research with fast, stopped, and reaccelerated beams that was successfully commissioned in May 2022. A key capability of FRIB is the production of an acceleration of the uranium beam, but this capability requires the facility to work at the design limits of the lowest charge-to-mass ratio and the highest power density on the beam intercepting devices. This paper presents techniques for overcoming the significant challenges in accelerating the uranium beam, culminating in the demonstration of 10.4 kW on target, and the discovery of three new isotopes. The high-power uranium beam enabled us to produce and identify <a:math xmlns:a="http://www.w3.org/1998/Math/MathML" display="inline"><a:mrow><a:mmultiscripts><a:mi mathvariant="normal">G</a:mi><a:mprescripts/><a:none/><a:mn>88</a:mn></a:mmultiscripts><a:mi mathvariant="normal">a</a:mi></a:mrow></a:math>, <e:math xmlns:e="http://www.w3.org/1998/Math/MathML" display="inline"><e:mrow><e:mmultiscripts><e:mi mathvariant="normal">A</e:mi><e:mprescripts/><e:none/><e:mn>93</e:mn></e:mmultiscripts><e:mi mathvariant="normal">s</e:mi></e:mrow></e:math>, and <i:math xmlns:i="http://www.w3.org/1998/Math/MathML" display="inline"><i:mrow><i:mmultiscripts><i:mi mathvariant="normal">S</i:mi><i:mprescripts/><i:none/><i:mn>96</i:mn></i:mmultiscripts><i:mi mathvariant="normal">e</i:mi></i:mrow></i:math>, within the first 24 h of operation. The successful uranium operation at FRIB sets a new record for accelerated uranium beam power above 10 kW and opens a new avenue of research with rare isotopes.
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