Dengue and Acute Kidney Injury

Dengue is the most widespread and rapidlygrowing vector-borne disease.1 An estimated2.5 billion people in 129 countries live inendemic tropical and subtropical regions areat risk of contracting dengue, with 105million people infected each year.2 Dengue isa viral infection transmitted by arthropods,whose vector is the female mosquito of thegenus Aedes, mainly Aedes aegypt.3 Theinfection is caused by an RNA virus of theFlaviviridae family, which has differentserotypes: DEN-1, DEN-2, DEN-3 and DEN4. This illness can range from subclinicalillness to flu-like symptoms and, although lesscommon, some patients develop the severeform of the disease, with severe bleeding,organ involvement and/or plasma leakagewith reduced blood volume. One of thecomplications of dengue, associated with highmorbidity and mortality rates, is acute kidneyinjury (AKI)