Polypharmacy, drug interactions, and iatrogenesis

This study aimed to comprehensively address therapeutic challenges in medication use among the elderly. The research utilized the Medication Use Instrument within the Falls Risk Assessment Battery (BARQ) to collect and analyze data on medication consumption. Sixty-three elderly individuals (X̅ = 67.40 ± 6.62 years) participated in the research. Results revealed that 20.63% were at high risk (score > 11), 3.17% at moderate risk (score 8-10), 15.89% at elevated risk (score 5-7), and 60.31% at low risk (score 0-4) of iatrogenic effects. Notably, a 16-week personalized exercise program led to a significant reduction in medication consumption, resulting in a decrease in high-risk participants (% = -75.39). In conclusion, this research highlights polypharmacy issues and associated complications in the elderly, emphasizing the potential for iatrogenic harm. Exercise programs show promise in mitigating these risks by reducing medication dependency and promoting overall well-being.