Triamcinolone and Dexamethasone Hypersensitivity: A Pediatric Case Report

Although corticosteroids are frequently used locally and systemically for their anti‐inflammatory and immunosuppressive effects, hypersensitivity is rare. In our case, a 16‐year‐old girl experienced anaphylaxis after injection of triamcinolone acetonide. The diagnosis of an IgE‐mediated allergy to triamcinolone acetonide was confirmed through intradermal testing. Intradermal tests and drug provocation tests were performed against other corticosteroids, but only the provocation test with dexamethasone resulted in delayed urticaria. This case indicates the potential for different types of hypersensitivity reactions to both triamcinolone and dexamethasone. Consequently, the importance of a comprehensive allergic evaluation with other corticosteroids is emphasized when a corticosteroid allergy is suspected.