526-P: Risk Factor for Prolonged Hospital Stay in Patient with Diabetes-Related Foot Infection Admitted to a Specialized Unit—A Retrospective Cohort Study

Introduction: Diabetes-related foot infections (DFI) demand high costs for health systems due prolonged hospital stay (PHS). We evaluated factors associated with PHS in patients hospitalized with DFI. Methods: We conducted a retrospective cohort study of patient>18 years hospitalized in a Peruvian hospital, during 2020 and 2021. Characteristic of patients and wounds were collected, such as the wound treatment (conservative care, minor/major amputation, and surgical debridement) and we evaluated its association with PHS, >10 days, using Poisson regression, to calculate adjusted relative risks (aRR) with their 95% confidence interval. Results: Data from 228 patients were analyzed, 76.3% were men, the mean age was 66 years, 56.6% had previous atherosclerotic cardiovascular disease (ASCVD). The median wound length was 3.5 cm, 59.5% pf patients had peripheral arterial disease, 50.5% received conservative wound care, and 49.6% had a prolonged hospital stay. Prolonged hospital stay was associated to wound length > 5 cm (aRR=1.63, 95%CI: 1.17 to 2.26), major amputation/surgical debridement (aRR=2.04, 95%CI: 1.4 to 2.97), minor amputation (aRR=1.79, 95%CI: 1.22 to 2.63), and previous ASCVD (aRR=1.4, 95%CI: 0.8 to 1.84). Conclusion: About half of the patients had a PHS, which was associated with longer wound length, type of wound treatment, and history of ASCVD. Disclosure E. Lopez-Huamanrayme: None. F.J. Pasquel: Research Support; Tandem Diabetes Care, Inc., Insulet Corporation, Dexcom, Inc., Ideal Medical Technologies, Novo Nordisk. Consultant; Dexcom, Inc., Medscape.