Hepatitis B virus enhancer 1 activates preS1 and preS2 promoters of integrated HBV DNA impairing HBsAg secretion

Zhiqiang Gu; Qianqian Jiang; Abudurexiti Abulaiti; Xiaojie Chen; Mingwei Li; Na Gao; Guiwen Guan; Ting Zhang; Danli Yang; Jingyuan Xi; Guangxin Yu; Shuhong Liu; Zhi‐Jun Zhu; Zhiliang Gao; Jingmin Zhao; Hongxin Huang; Xiangmei Chen; Fengmin Lu

doi:10.1016/j.jhepr.2024.101144

Abstract

The expression of HBsAg from integrated HBV DNA limits the achievement of functional cure for chronic hepatitis B. Thus, characterising the unique expression and secretion of HBsAg derived from integrated HBV DNA is of clinical significance.

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Gu et al. (2024) studied this question.

synapsesocial.com/papers/68e64d72b6db6435875de2fc https://doi.org/10.1016/j.jhepr.2024.101144

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Hepatitis B virus enhancer 1 activates preS1 and preS2 promoters of integrated HBV DNA impairing HBsAg secretion

Abstract

Discussion

Cite This Study

Hepatitis B virus enhancer 1 activates preS1 and preS2 promoters of integrated HBV DNA impairing HBsAg secretion

Abstract

Discussion

Cite This Study

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