Identification of genetic modifiers of Huntington’s disease somatic CAG repeat instability by in vivo CRISPR-Cas9 genome editing

Ricardo Mouro Pinto; Ryan Murtha; António Azevedo; Cameron Douglas; Marina Kovalenko; Jessica Ulloa; Steven Crescenti; Zoe Burch; Esaria Oliver; Antonia Vitalo; Eduarda Mota‐Silva; Marion J. Riggs; Kevin Correia; Emanuela Elezi; Brigitte Demelo; Jeffrey B. Carroll; Tammy Gillis; James F. Gusella; Marcy E. MacDonald; Vanessa C. Wheeler

doi:10.1101/2024.06.08.597823

Abstract

Huntington's disease (HD), one of >50 inherited repeat expansion disorders (Depienne and Mandel, 2021), is a dominantly-inherited neurodegenerative disease caused by a CAG expansion in

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synapsesocial.com/papers/68e6585fb6db6435875e705c https://doi.org/10.1101/2024.06.08.597823

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Abstract

Huntington's disease (HD), one of >50 inherited repeat expansion disorders (Depienne and Mandel, 2021), is a dominantly-inherited neurodegenerative disease caused by a CAG expansion in

Identification of genetic modifiers of Huntington’s disease somatic CAG repeat instability by in vivo CRISPR-Cas9 genome editing

Abstract

Discussion

Cite This Study

Identification of genetic modifiers of Huntington’s disease somatic CAG repeat instability by in vivo CRISPR-Cas9 genome editing

Abstract

Discussion

Cite This Study

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