Laboratory study reveals ginsenoside Rg3 induces proliferation and reduces apoptosis in mesangial cells via the miR-216a-5p/MAPK pathway, suggesting therapeutic potential for diabetic kidney disease.
Ginsenoside Rg3 is an active saponin isolated from ginseng, which can reduce renal inflammation. However, the role and mechanism of Rg3 in diabetic kidney disease (DKD) are far from being studied.
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Chen et al. (2024) studied this question.
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