Decreased Memory-related Regional Cerebral Perfusion in Severe Obstructive Sleep Apnoea With a Mild Cognitive Impairment v1

We will use arterial spin labeling (ASL) technology to quantify and evaluate abnormal changes in resting state cerebral blood perfusion in patients with obstructive sleep apnea (OSA) with cognitive impairment (CI) and to explore the underlying neuropathological mechanisms in patients with OSA and CI (OSA-CI). The findings are basically in line with our study hypothesis.OSA-CI patients, similar to AD and MCI, may initially present with decreased memory function. The progressive aggravation of hemodynamic abnormalities in the bilateral inferior temporal gyrus and left lingual gyrusin OSA patients may contribute to decreased brain memory function and subsequent memory dysfunction.