Diffuse Intrinsic Pontine Glioma (DIPG) is a proliferative brain tumor that is aggressive in nature and rapid growing. DIPG predominantly affects the pons, a part of the brain stem that is responsible for regulating vital physiologic functions such as breathing, heart rate, and hemodynamic stability. In the United States, about 300 children are diagnosed with DIPG each year, affecting children between 5 and 10 years of age, but may occur in younger populations and in some cases, teenage populations. DIPGs typically have a lethal prognosis due to the inability to surgically resect tumors safely, and current drug and radiation therapies ultimately being ineffective.
No takes yet. Share an insight, caveat, or question.
Radwa Clarissa Omar (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: