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June 4, 2024Open Access

Supplementary Figure 2 from The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity

J. K. Lim Ryan Rodriguez Katherine Williams John Silva Alan G. Gutierrez Paul Tyler Faezzah Baharom Tao Sun Eva Lin Scott E. Martin Brandon D. Kayser Robert J. Johnston Ira Mellman Lélia Delamarre Nathaniel R. West Sören Müller Yan Qu Klaus Heger

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Abstract

Supplementary Figure 2. Tumor-intrinsic TREX1 loss impairs CT26 tumor growth in immunocompetent mice in a cGAS dependent manner.

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Lim et al. (2024) studied this question.

synapsesocial.com/papers/68e664bab6db6435875f13e9 https://doi.org/10.1158/2326-6066.25964546.v1

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 2 from The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity2024
2Supplementary Figure 1 from The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity2024
3Supplementary Figure 1 from The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity2024
4Supplementary Figure 3 from The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity2024
5Supplementary Figure 3 from The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity2024

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Supplementary Figure 6 from The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity2024
Supplementary Figure 6 from The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity2024
Supplementary Figure 4 from The Exonuclease TREX1 Constitutes an Innate Immune Checkpoint Limiting cGAS/STING-Mediated Antitumor Immunity2024