Antisynthetase Syndrome with Anti-Jo-1 Antibodies Following Oxford-Astrazeneca COVID-19 Vaccination: Uncommon Case Report

Anti-synthetase syndrome (ASS) is an idiopathic inflammatory myopathy (IIM) with autoantibodies against one of many aminoacyl transfer RNA (tRNA) synthetases. Since the widespread introduction of the Sars-Cov 2 vaccines, a number of adverse reactions have been reported. In terms of these vaccines, Oxford AstraZeneca vaccines have been responsible for various side effects, but their benefits outweigh the risks. Cases of IIM following vaccination are rarely reported in the literature. Here we report a case of ASS in a patient who received the Oxford-Astrazeneca's Sars-Cov 2 vaccine.