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June 3, 2024Open Access

Supplementary Figure S3 from A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma

James Brugarolas Gregory Obara Kathryn E. Beckermann Brian I. Rini Elaine T. Lam James Hamilton Thomas Schluep Min Yi So C. Wong Zhongping Lily Mao Érick Gamelin Nizar M. Tannir

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Abstract

Figure S3: ARO-HIF2 Plasma Concentration-Time Profiles by Treatment and Dosing Week

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Brugarolas et al. (2024) studied this question.

synapsesocial.com/papers/68e66839b6db6435875f3cfd https://doi.org/10.1158/1078-0432.25956248

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S3 from A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma2024
2Supplementary Figure S4 from A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma2024
3Supplementary Figure S4 from A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma2024
4Supplementary Figure S2 from A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma2024
5Supplementary Figure S2 from A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma2024

Supplementary Figure S7 from A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma2024
Supplementary Figure S7 from A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma2024
Supplementary Methods S1 from A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma2024