The Importance of Near Follow-Up in Perianal Fistula

Anal canal mucinous adenocarcinoma constitutes 2-3% of anal canal tumors. It is very rare to see perianal fistula and anal canal mucinous adenocarcinoma (MA) together. The underlying pathophysiology leading to malignant transformation is still not clear. For MA to develop, the perianal fistula must be at least 10 years old, and this is one of the diagnostic criteria.[1] [2] However, Michihiro Koizumi et al. They revealed the existence of a perianal fistula-related MA with a 3-year follow-up.[3]