Association between body mass index and physical activity among prostate cancer survivors.

5029 Background: Prostate cancer (PCa) has become a chronic disease due to advances in treatment and earlier detection. Therefore, factors that modify survival post‐diagnosis are important. Obesity is associated with increased PCa recurrence and mortality. Thus, interventions that reduce obesity, e.g., physical activity (PA) may prolong survival. We assessed the association between body mass index (BMI) and PA among prostate cancer survivors as well as other modifiable predictors of PA. Methods: We conducted a cross-sectional analysis of data from the 2018-22 Behavioral Risk Factor Surveillance System, an ongoing national population-based telephone survey conducted in the U.S. The outcome variable is PA after PCa diagnosis. We classified BMI (exposure) using standard cut points defined by the WHO. Multivariable weighted logistic regression was used to examine the association between BMI and PA adjusting for confounders. All significance tests were two-sided and p-value < 0.05 was significant. The data were analyzed accounting for the complex sample survey design. Results: Of the 4,944 prostate cancer respondents, 78% were 65 years or older and 69% were White. 23% were obese class I and 11% were obese class II & III. Obese class I and obese class II & III respondents were significantly less likely to report PA (OR=0.48; 95% CI: 0.28-0.84 and OR=0.37; 95% CI: 0.20-0.67; respectively). Men who received a summary of their cancer treatment were significantly more likely to report PA (OR=1.53; 95% CI: 1.03-2.28). Current smokers were less likely to report PA (OR=0.50; 95% CI: 0.26-0.96). Conclusions: Obese men and current smokers were less likely to report PA. Men who received a summary of their cancer treatment were more likely to report PA. Healthcare providers should talk to their patients about the benefit of exercising and refer patients to available exercise programs.