Potential Therapeutic Benefits of Using the BeCare MS Link App Frequently

Objective: BeCare MS Link App quantitatively measures neurologic function on a mobile phone and calculates Expanded Disability Status Scale (EDSS) through AI.Previous peer-reviewed studies demonstrated a convergence validity of the clinical EDSS.The primary objective of this study is to assess the therapeutic benefits of frequent use of the BeCareLink App activities.Design/Methods: Data was collected from the use of the BeCareLink mobile device app by subjects with MS.Subjects were enrolled over three months beginning at the time of IRB approval.Patients were divided into two groups: the first group of 100 patients was asked to perform all the activities 3 or more days per week (Frequent Use Arm), and the second group of 25 patients was asked to perform all the activities only twice during the 12-week period-day 0 and day 90 (Infrequent Use Arm). Results:The results show that of subjects with very mild disease (EDSS of 0.5-1.5),33% had unchanged EDSS scores, 38% showed improvement and 29% worsened when remeasured 3 months from the initial date.Of Patients with more significant disease (EDSS of > 2.0), 70% remained clinically unchanged or improved and 30% worsened.Infrequent users showed less significant change in function (25% improved, 36% stayed the same, and 39% worsened).Conclusions: Frequent use of BeCareLink's activities may have a therapeutic benefit for patients with demonstrable disability.