Sharp corners of castleman diseaseclinical case

Castleman’s disease (CD) is a very rare condition that can occur at any age and affects 16:100000 patients/years. CD is characterized by systemic inflammatory symptoms, generalized lymphadenopathy, polyclonal lymphocyte proliferation and multiple organ system dysfunctions, often associated with autoimmune manifestations, which may precede diagnosis, may be identified concurrently or may follow diagnosis. The given article presents the major and minor criteria on the basis of which the diagnosis is established, as well as the importance of interdisciplinary work in identifying and making the differential diagnosis of the Castleman disease.