Granular cell tumors are rare soft tissue tumors with neural origin that present malignant potential. Perianal granular cell tumors with only subcutaneous involvement are uncommonly presented in the literature. Herein, we present the case of a 49-year-old female patient with perianal granular cell tumor of the buttock. The patient underwent successful surgical resection and remains under close postoperative follow-up. There is no standard diagnostic algorithm for these tumors, and imaging provides little benefit. Histopathology and immunohistochemical staining are necessary for the accurate diagnosis of granular cell tumors.
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Marcucci et al. (2024) studied this question.
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