Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes

Bruna Paulsen; Sabrina Piechota; Ferran Barrachina; Alexa Giovannini; Simone Kats; Kathryn Potts; Graham Rockwell; Maria Marchante; Samantha L. Estevez; Alexander D. Noblett; Alexandra B Figueroa; Caroline Aschenberger; Dawn A. Kelk; Marcy Forti; Shelby Marcinyshyn; Klaus Wiemer; Marta Sanchez; Pedro Belchin; Joseph A. Lee; Erkan Büyük; Rick E. Slifkin; Merrick Pierson Smela; Patrick R.J. Fortuna; Pranam Chatterjee; David H. McCulloh; Alan B. Copperman; Daniel Ordonez-Perez; Joshua U. Klein; Christian Kramme

doi:10.1007/s10815-024-03143-4

Abstract

Determine if the gene expression profiles of ovarian support cells (OSCs) and cumulus-free oocytes are bidirectionally influenced by co-culture during in vitro maturation (IVM).

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Paulsen et al. (2024) studied this question.

synapsesocial.com/papers/68e67968b6db643587603d4c https://doi.org/10.1007/s10815-024-03143-4

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Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes

Abstract

Discussion

Cite This Study

Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes

Abstract

Discussion

Cite This Study

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