Chinese health officials kept an eye on a cluster of pneumonia cases that occurred in the Chinese city of Wuhan (Hubei, China) in December 2019.The novel coronavirus severe acute respiratory syndrome coronavirus-2 pathogen, often referred to as COVID-19, was the cause of this.The goal of this review is to concentrate on the neurological manifestations of the 2019 coronavirus disease and to describe the existing published data as well as ongoing trials.Scopus, PubMed, and the Cochrane Library were searched from their inception until May of 2020 for any published papers using the terms "COVID-19" and "neurological disorders."To make sure no other clinical trials were overlooked, a separate search of Google Scholar was also conducted.The author examined the list of references of the research that was cited or relevant reviews that were recognized through the trial to make sure that the literature was sufficiently covered.If there were many publications on the same clinical trial, the most recent and thorough report was the one that was chosen.A search of all three databases yielded a total of 89 articles.Twenty-two full-text papers were reviewed for eligibility, and twelve were found to be ineligible.There were 290 patients reported to have neurological symptoms throughout all investigations.All central nervous system (CNS) signs, except headache, were more common in severe cases, according to the COVID-19 severity classification.Adults only participated in all of the included investigations.The neurological symptoms of the 2019 coronavirus disease should be studied because of the potential consequences they hold; however, many studies reveal that the psychosocial symptoms are far more common.It is still unknown from the research conducted so far whether or not brain infection is a subsequent symptom of COVID-19.However, if the brainstem were to become infected, it might disrupt normal breathing processes and throw the body out of balance.
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