Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 26, 2024Open Access

Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death.

View Full Paper
Ask AI
Bookmark
Share

Authors

PMPablo MartínezBaylor College of MedicineMSMónica SilvaUniversity of ChileSASebastián AbarzúaUniversidad Andrés Bello

Discussion

Loading...

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Martínez et al. (2024) studied this question.

synapsesocial.com/papers/68e6859fb6db64358760e7dfhttps://doi.org/10.1101/2024.05.24.595817
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling2015 · 101 citations
  2. 2Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice2010 · 316 citations
  3. 3Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow2020 · 58 citations
  4. 4Progressive motor unit loss in the G93A mouse model of amyotrophic lateral sclerosis is unaffected by gender2009 · 43 citations