Therapeutic Effect of Vastyamantak Ghrita Uttarbasti in Recurrent Urethral Stricture: A Case Report

Urethral stricture, commonly resulting from infections, trauma, or iatrogenic causes, continues to present therapeutic challenges despite advances in surgical interventions such as urethroplasty, visual internal urethrotomy and dilatation. In Ayurvedic literature, particularly in the Sushruta Samhita, this condition is described under the term Mutrasanga. Although urethroplasty remains the gold standard for treatment, the high recurrence rate associated with current surgical modalities highlights the need for adjunct or alternative therapeutic strategies. This case study explores the Ayurvedic management of recurrent urethral stricture through the administration of Vastyamantaka Ghrita via Uttarbasti (transurethral medicated oil instillation). A 44-year-old man with a history of recurrent strictures and unsuccessful outcomes from multiple dilatation procedures was treated with Uttarbasti every fourth day over an eight-week period, initiated post-dilatation. The intervention resulted in significant clinical improvement, including an increase in maximum urinary flow rate (Qmax) from 5.1 mL/s to 14 mL/s, a decrease in Post-Void Residual (PVR) urine volume from 230 mL to 55 mL, and normalisation of urinary frequency. Post-treatment imaging confirmed the absence of residual stricture. These findings suggest that Vastyamantaka Ghrita administered via Uttarbasti may represent a promising, non invasive therapeutic option for managing recurrent urethral stricture and potentially reducing its recurrence.