Nonrandomized clinical trial evaluates targeted therapies and immunotherapies in metastatic cancer, highlighting clinical potential for off-label precision oncology.
The Drug Rediscovery Protocol (DRUP) is a Dutch, pan-cancer, nonrandomized clinical trial that aims to investigate the efficacy and safety of targeted and immunotherapies outside their registered indication in patients with advanced or metastatic cancer.
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Mohammad et al. (2024) studied this question.
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