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Abstract An application of multi‐component milling is described to achieve a decolorization by dismantling the orange‐red zwitterionic cocrystal ( PDA )∙( APAP ) (where PDA = 2,4‐pyridinedicarboxylic acid, APAP = acetaminophen) using n,n ′‐BPE ( BPE = trans ‐1,2‐bis( n ‐pyridylethylene and for n = n ′ = 3 or 4). Each of n , n ′‐BPE forms a colorless hydrogen‐bonded cocrystal with PDA .
Ezekiel et al. (Fri,) studied this question.
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